The Need for Neddylation: A Key to Achieving NED in Uveal Melanoma
نویسندگان
چکیده
منابع مشابه
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15 صفحه اولUveal Melanoma
The eye’s uveal tract consists of the iris, ciliary body, and choroid. It contains a population of melanocytes. Uveal melanomas develop from melanocytes that reside within the stroma of the choroid, ciliary body or iris. The choroid is the vascular part of the human eye between retina and sclera. Though accurate measurements of the choroidal blood flow is difficult, it is known that choroid is ...
متن کاملUveal Melanoma.
BACKGROUND: Malignant melanoma of the uveal tract is a rare malignancy but a significant cause of mortality and visual loss. Approximately 50% of patients diagnosed with a melanoma of the choroid or ciliary body will die of the disease within 15 years of enucleation. METHODS: The author reviewed the current literature on the clinical findings, epidemiology, and treatment of uveal melanoma. RESU...
متن کاملUveal Melanoma
Uveal melanoma is the most common primary intraocular malignancy and the leading primary intraocular disease which can be fatal in adults. In this paper epidemiologic, pathogenetic, and clinical aspects of uveal melanoma are discussed. Despite the advance in local ocular treatments, there has been no change in patient survival for three decades. Development of metastases affects prognosis signi...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2018
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-18-0020